Schaefer et al. (2025) Microbiology Resource Announcements

RefAHL: A Curated Quorum Sensing Reference Linking Diverse LuxI-Type Signal Synthases with Their Acyl-Homoserine Lactone Products

Schaefer AL, Murdock EG, Pelletier DA, Harwood CS, Greenberg EP, Puri AW

2025, Microbiology Resource Announcements, https://doi.org/10.1128/mra.00407-25

Abstract

Some bacteria use acyl-homoserine lactone (AHL) signals in quorum sensing, a type of cell-cell communication. Here, we present “RefAHL,” an updated, curated collection of LuxI-type AHL synthases with their AHL products and associated metadata. RefAHL is publicly available as a community resource to help catalog LuxI-type diversity encoded in (meta) genomic data.

Citation

Schaefer AL, Murdock EG, Pelletier DA, Harwood CS, Greenberg EP, Puri AW. (2025) RefAHL: A Curated Quorum Sensing Reference Linking Diverse LuxI-Type Signal Synthases with Their Acyl-Homoserine Lactone Products. Microbiology Resource Announcements. DOI:10.1128/mra.00407-25