Sipros/ProRata: A Versatile Informatics System for Quantitative Community Proteomics
Wang Y, Ahn TH, Li Z, Pan C
2013, Bioinformatics, https://doi.org/10.1093/bioinformatics/btt329
Abstract
Sipros/ProRata is an open-source software package for end-to-end data analysis in a wide variety of community proteomics measurements. A database-searching program, Sipros 3.0, was developed for accurate general-purpose protein identification and broad-range post-translational modification searches. Hybrid Message Passing Interface/OpenMP parallelism of the new Sipros architecture allowed its computation to be scalable from desktops to supercomputers. The upgraded ProRata 3.0 performs label-free quantification and isobaric chemical labeling quantification in addition to metabolic labeling quantification. Sipros/ProRata is a versatile informatics system that enables identification and quantification of proteins and their variants in many types of community proteomics studies.
Citation
Wang Y, Ahn TH, Li Z, Pan C. (2013) Sipros/ProRata: A Versatile Informatics System for Quantitative Community Proteomics. Bioinformatics. DOI:10.1093/bioinformatics/btt329