Some bacteria use acyl-homoserine lactone (AHL) signals in quorum sensing, a type of cell-cell communication. Here, we present “RefAHL,” an updated, curated collection of LuxI-type AHL synthases with their AHL products and associated metadata. RefAHL is publicly available as a community resource to help catalog LuxI-type diversity encoded in (meta) genomic data.

Citation

Amy L Schaefer, Ethan G Murdock, Dale A Pelletier, Caroline S Harwood, E Peter Greenberg, Aaron W Puri (2025). RefAHL: A Curated Quorum Sensing Reference Linking Diverse LuxI-Type Signal Synthases with Their Acyl-Homoserine Lactone Products. Microbiology Resource Announcements, 14:e00407-25. DOI: 10.1128/mra.00407-25