Sipros/ProRata: a versatile informatics system for quantitative community proteomics
Yingfeng Wang, Tae-Hyuk Ahn, Zhou Li, and Chongle Pan
21 June 2013, Bioinformatics 29(16): 2064-2065; doi: 10.1093/bioinformatics/btt329
Sipros/ProRata is an open-source software package for end-to-end data analysis in a wide variety of community proteomics measurements. A database-searching program, Sipros 3.0, was developed for accurate general-purpose protein identification and broad-range post-translational modification searches. Hybrid Message Passing Interface/OpenMP parallelism of the new Sipros architecture allowed its computation to be scalable from desktops to supercomputers. The upgraded ProRata 3.0 performs label-free quantification and isobaric chemical labeling quantification in addition to metabolic labeling quantification. Sipros/ProRata is a versatile informatics system that enables identification and quantification of proteins and their variants in many types of community proteomics studies.
Yingfeng Wang, Tae-Hyuk Ahn, Zhou Li, and Chongle Pan Sipros/ProRata: a versatile informatics system for quantitative community proteomics Bioinformatics 2013 29: 2064-2065.